Horatio Caine (David Caruso) requests that Las Vegas CSI Ray Langston (Laurence Fishburne) come to Miami when a severed leg found in the Everglades is traced back to a girl who went missing in Las Vegas a week earlier.

Tonight's episode of "CSI: Miami" is the first of a three-part story that takes Langston from Miami to New York and back to Las Vegas.

"[It is about] human trafficking … girls who are forced into prostitution," Fishburne tells ET. "Their organs are harvested. They have to become surrogate moms. They get transported across the country on the interstate."

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